Nannan L, Gsell W, Belderbos S, Gallet C, Wouters J, Brassart-Pasco S, Himmelreich U, Brassart B.  A multimodal imaging study to highlight elastin-derived peptide pro-tumoral effect in a pancreatic xenograft model.  Br J Cancer.  2023

Colin-Pierre C, Untereiner V, Sockalingum GD, Ramont L, Brézillon S.  Investigation of Glypican-4 and -6 by Infrared Spectral Imaging during the Hair Growth Cycle.  Int J Mol Sci.  2023

Colin-Pierre C, El Baraka O, Ramont L, Brézillon S.  An innovative 3D-printed insert designed to enable straightforward 2D and 3D cell cultures.  J Vis Exp.  2023


Fuselier C, Dufay E, Berquand A, Terryn C, Bonnomet A, Molinari M, Martiny L, Schneider C.  Dynamized ultra-low dilution of Ruta graveloens disrupts membrane organization and decreases migration of melanoma cancer cell.  Cell adhesion & migration.  2023

Langlois B, Martin J, Schneider C, Hachet C, Terryn C, Rioult D, Martiny L, Théret L, Salesse S, Dedieu S.  LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion.  Front Oncol.  2022

I Toumi, S Yatouji, N Borie, S Remy, J H Renault, L Chazee, M Hammami, L Martiny, E Devarenne-Charpentier, H El Btaouri.  Anti-tumoral effect of Thymelaea hirsuta L extracts in colorectal cancer cells.  Anticancer Agents Med Chem.  2022


Colin-Pierre C, Berthélémy N, Belloy N, Danoux L, Bardey V,  Rivet R, Mine S, Jeanmaire C, Maquart FX, Ramont L, Brézillon S.  The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis.  Frontiers in Cell and Developmental Biology.  2021

Nizet P, Untereiner V, Sockalingum GD, Proult I, Terryn C, Jeanne A, Nannan L, Boulagnon-Rombi C, Sellier C, Rivet R, Ramont L, Brézillon S.  Assessment of ovarian tumor growth in wild-type and lumican-deficient mice: insights using infrared spectral imaging, histopathology, and immunohistochemistry.  Cancers.  2021

Jeanne A*, Sarazin T*, Charlé M, Moali C, Fichel C, Boulagnon-Rombi C, Callewaert M, Andry MC, Diesis E, Delolme F, Rioult D, Dedieu S.  Targeting ovarian carcinoma with TSP-1:CD47 antagonist TAX2 activates anti-tumor immunity.  Cancers.  2021

Campion O, Thevenard Devy J, Billottet C, Schneider C, Etique N, Dupuy JW, Raymond A, Boulagnon Rombi C, Meunier M, Djermoune EH, Lelièvre E, Wahart A, Bour C, Hachet C, Cairo S, Bikfalvi A, Dedieu S, Devy J.  LRP-1 matricellular receptor involvement in triple negative Breast Cancer Tumor Angiogenesis.  Biomedicines.  2021

Fuselier C, Quemener S, Dufay E, Bour C, Boulagnon-Rombi C, Bouland N, Djermoune E-H, Devy J, Martiny L, Schneider C.  Anti-tumoral and anti-angiogenic effects of low-diluted Phenacetinum on melanoma.  Frontiers in Oncology.  2021

Durand M, Lelièvre E, Chateau A, Berquand A, Laurent G, Carl P, Roux S, Chazée L, Bazzi R, Eghiaian F, Rondé P, Jubréaux J, Barberi-Heyob M, Chastagner P, Devy J*, Pinel S*.  The detrimental invasiveness of glioma cells controlled by gadolinium chelate-coated gold nanoparticles.  Nanoscale.  2021

Oudart JB, Villemin M, Brassart B, Sellier C, Terryn C, Dupont-Deshorgue A, Monboisse JC, Maquart FX, Ramont L, Brassart-Pasco S.  F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through alphavbeta3 and alpha5beta1 integrin interaction.  Cell Adh Migr.  2021

Karamanou K, Franchi M, Proult I, Rivet R, Vynios D, Brézillon S.  Lumican Inhibits In Vivo Melanoma Metastasis by Altering Matrix-Effectors and Invadopodia Markers.  Cells.  2021

Colin-Pierre C, Untereiner V, Sockalingum GD, Berthélémy N, Danoux L, Bardey V, Mine S, Jeanmaire C, Ramont L, Brézillon S.  Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 during Hair Growth Cycle.  Biomolecules.  2021


Le Cao C., Bennasroune A., Collin G., Hachet C., Lehrter V., Rioult D., Dedieu S.*, Morjani H.*, Appert-Collin A*. LRP-1 promotes colon cancer cell proliferation in 3D collagen matrices by mediating DDR1 endocytosis. Frontiers in Dev. Biol, 2020, 8:412.

Brassart-Pasco S, Brézillon S, Brassart B, Ramont L, Oudart J-B, Monboisse J-C. Tumor microenvironment: extracellular matrix alterations influence tumor progression. Frontiers in Oncology, 2020 ;10:397.

Mohamed HT, Untereiner V, Cinque G, Ibrahim SA, Götte M, Nguyen NQ, Rivet R, Sockalingum GD, Brézillon S. Infrared Microspectroscopy and Imaging Analysis of Inflammatory and Non-Inflammatory Breast Cancer Cells and Their GAG Secretome. Molecules. 2020; 25(18):4300.

Nannan L, Untereiner V, Proult I, Boulagnon-Rombi C, Colin-Pierre C,  Sockalingum GD, Brézillon S. Label-free infrared spectral histology of skin tissue Part I: Impact of lumican on extracellular matrix integrity. Frontiers in Cell and Developmental Biology, 2020, 8:320.

Blandin AF, Cruz Da Silva E., Mercier MC, Glushonkov LO, Didier P. , Dedieu S., Schneider C., Thevenard-Devy J. , Etienne-Selloum N., Dontenwill M., Choulier L., Lehmann M. Gefitinib induces EGFR and α5β1 integrin co-endocytosis in glioblastoma cells. Cell Mol Life Sci., 2020.

Lefebvre T, Rybarczyk P, Bretaudeau C, Cousin R, Brassart-Pasco S, Chatelain D, Dhennin-Duthille I, Ouadid-Ahidouch H, Brassart B*, Gautier M*. TRPM7/RPSA complex regulates pancreatic cancer cell migration. Frontiers in Cell and Developmental Biology, 2020, 8:549.

Kumar AV, Brézillon S, Untereiner V, Sockalingum GD, Katakam SK, Mohamed HT, Kemper B, Greve B,  Mohr B, Goycoolea F, Kiesel L, Pavao M,  Motta J, Götte M. HS2ST1-dependent signaling pathways determine breast cancer cell viability, matrix interactions and invasive behavior. Cancer Science, 2020; 111(8):2907-22.

Le Cao C., Bennasroune A., Langlois B., Salesse S., Boulagnon-Rombi C., Morjani H., Dedieu S.*, Appert-Collin A*. Functional interplay between collagen network and cell behavior within tumor microenvironment in colorectal cancer. Frontiers in Oncology 2020, 2020, 8:412.

Bretaudeau C, Baud S, Dupont-Deshorgue A, Cousin R, Brassart B, Brassart-Pasco S. Elastin-derived peptide, AG-9, increases tongue carcinoma in a RPSA-dependent manner and this effect is abolished by (−)-epigallocatechin-3-gallate. Biomolecules. 2020 Dec 30;11(1):39.

Vautrin-Glabik A, Devy J, Bour C, Baud S, Choulier L, Hoarau A, Dupont-Deshorgue A, Sellier C, Brassart B, Oudart JB, Ramont L, Monboisse JC, Brassart-Pasco S. Angiogenesis Inhibition by a Short 13 Amino Acid Peptide Sequence of Tetrastatin, the α4(IV) NC1 Domain of Collagen IV. Front Cell Dev Biol. 2020: 11, 8:775.

Karamanou K., Franchi M., Vynios D., Brézillon S. Epithelial-to-mesenchymal transition and invadopodia markers in breast cancer: Lumican a key regulator. Seminars in Cancer Biology, 2020 May;62:125-133.

Brassart-Pasco S, Dalstein V, Brassart B, Clavel C, Oudart JB. Immunotherapy in NSCLC: from targeted molecules to resistance patterns. Pharmacogenomics, 21(10):705-720.

Campion O.*, Al Khalifa T.*, Langlois B., Thevenard-Devy J., Salesse S., Savary K., Schneider C., Etique N., Dedieu S.*, Devy J*. Contribution of the low-density lipoprotein receptor family to breast cancer progression. Frontiers in Oncology, 2020, 10:882.

Brézillon S, Untereiner V, Mohamed HT, Ahallal E, Proult I, Nizet P, Sockalingum GD. Label-free infrared spectral histology of skin tissue Part II: Impact of Lumican-derived peptides on melanoma development. Frontiers in Cell and Developmental Biology, 2020, 8:377.

Karamanou K., Franchi M., Maurizio O., Passi A., Vynios D., Brézillon S. Evaluation of lumican effects in morphology of invading breast cancer cells, expression of integrins and downstream signaling. FEBS J., 2020, 287(22):4862-4880.

Papiewska-Pająk I, Krzyżanowski D, Katela M, Rivet R, Michlewska S, Przygodzka P, Kowalska MA, Brézillon S. Glypican-1 Level Is Elevated in Extracellular Vesicles Released from MC38 Colon Adenocarcinoma Cells Overexpressing Snail. Cells. 2020 Jun 30;9(7):1585

Slimano F, Djerada Z, Guerin J, Bellouch MI, Brassart-Pasco S, Dukic S. Intratumoral distribution of YSNSG cyclopeptide in a mouse melanoma model using microdialysis. Eur J Pharm Sci. 2020; 143:105201.

Nannan L, Oudart JB, Monboisse JC, Ramont L, Brassart-Pasco S, Brassart B. Extracellular Vesicle-dependent cross-talk in pancreatic Cancer. Frontiers in Oncology, 2020, 10:1456.


Daubon T., Léon C., Clarke K., Andrique L., Salabert L., Darbo E., Pineau R., Guerit S., Maître M., Dedieu S, Jeanne A., Bailly S., Feige J.J., Miletic H., Rossi M., Bello L., Falciani F., Bjerkvig R., Bikfalvi A. Deciphering the complex role of thrombospondin-1 in glioblastoma development. Nature Communications 2019, 10(1):1146.

Brassart B, Da Silva J, Donet M, Seurat E, Hague F, Terryn C, Velard F, Michel J, Ouadid-Ahidouch H, Monboisse JC, Hinek A, Maquart FX, Ramont L, Brassart-Pasco S. Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA. Br J Cancer 2019, 120(4):453-465.

Fuselier C, Terryn C, Berquand A, Crowet J-M, Bonnomet A, Molinari M, Dauchez M, Martiny L, Schneider C. Low-diluted Phenacetinum disrupted the melanoma cancer cell migration. Scientific Reports 2019, 9 (1).

Perrot G, Colin-Pierre C, Ramont L, Proult I, Garbar C, Bardey V, Jeanmaire C, Mine S, Danoux L, Berthélémy N, Maquart FX, Wegrowski Y, Brézillon S. Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. Exp Gerontol., 126:110693.

Jeanne A, Rattenbach R, Lamensdorf I, Martiny L, Martin C, Dedieu S. Thrombospondin-targeting TAX2 peptide impairs tumor growth in preclinical mouse models of childhood neuroblastoma. Pediatr Res. 2019 Apr;85(5):734.

Blons H, Garinet S, Laurent-Puig P, Oudart JB.  Molecular markers and prediction of response to immunotherapy in non-small cell lung cancer, an update. J Thorac Dis. 2019 Jan;11(Suppl 1):S25-S36.

Jiménez Sánchez G, Maury P, Stefancikova L, Campion O, Laurent G, Chateau A, Bouraleh Hoch F, Boschetti F, Denat F, Pinel S, Devy J, Porcel E, Lacombe S, Bazzi R, Roux S. Fluorescent Radiosensitizing Gold Nanoparticles. Int J Mol Sci. 2019 Sep 18;20(18). pii: E4618.

Henriet P, Emonard H. Matrix metalloproteinase-2: Not (just) a "hero" of the past. Biochimie. 2019 Nov;166:223-232.

Pietraszek-Gremplewicz K., Karamanou K., Niang A., Dauchez M., Belloy N., Maquart FX., Baud S., Brézillon S. Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners? Matrix Biol. 2019 Jan;75-76:271-285.


Berquand A, Meunier M, Thevenard-Devy J, Ivaldi C, Campion O, Dedieu S, Molinari M, Devy J. A gentle approach to investigate the influence of LRP-1 silencing on the migratory behavior of breast cancer cells by atomic force microscopy and dynamic cell studies. Nanomedicine, 18:359-370.

Chièze L, Le Cigne A, Meunier M, Berquand A, Dedieu S, Devy J, Molinari M. Quantitative characterization of single-cell adhesion properties by atomic force microscopy using protein-functionalized microbeads. J Mol Recognit., 32(3):e2767.

Cattin S., Ramont L., Rüegg C. Characterization andIn Vivo Validation of a Three-Dimensional Multi-Cellular Culture Model to Study Heterotypic Interactions in Colorectal Cancer Cell Growth, Invasion and Metastasis. Front Bioeng Biotechnol. 2018 Jul 17;6:97

Lambert E, Fuselier E, Ramont L, Brassart B, Dukic S, Oudart JB, Dupont-Deshorgue A, Sellier C, Machado C, Dauchez M, Monboisse JC, Maquart FX, Baud S, Brassart-Pasco S. Conformation-dependent binding of a Tetrastatin peptide to αvβ3 integrin decreases melanoma progression through FAK/PI3K/Akt pathway inhibition. Sci Rep. 2018 Jun 29;8(1):9837.

Mohamed HT, Untereiner V, Proult I, Ibrahim SA, Götte M, El-Shinawi M, Mohamed MM, Sockalingum GD, Brézillon S. Characterization of inflammatory breast cancer: a vibrational microspectroscopy and imaging approach at the cellular and tissue level. Analyst. 2018 Dec 3;143(24):6103-6112.

Karamanou K, Perrot G, Maquart FX, Brézillon S. Lumican as a multivalent effector in wound healing. Adv Drug Deliv Rev. 2018 Apr;129:344-351.

Da Silva J, Lameiras P, Beljebbar A, Berquand A, Villemin M, Ramont L, Dukic S, Nuzillard JM, Molinari M, Gautier M, Brassart-Pasco S, Brassart B. Structural characterization and in vivo pro-tumor properties of a highly conserved matrikine. Oncotarget. 2018 Apr 3;9(25):17839-17857.

Boulagnon-Rombi C., Schneider C., Leandri C., Jeanne A., Grybek V., Marchal Bressenot A., Barbe C., Marquet B., Nasri S., Coquelet C., Fichel C., Bouland N., Bonnomet A., Kianmanesh R., Lebre A.S., Bouche O., Diebold M.D., Bellon G., Dedieu S. LRP1 expression in colon cancer predicts clinical outcome. Oncotarget. 2018 Jan 13;9(10):8849-8869.

Keklikoglou I., Kadioglu E., Bissinger S., Langlois B., Bellotti A., Orend G., Ries CH., De Palma M. Periostin Limits Tumor Response to VEGFA Inhibition. Cell Rep. 2018 Mar 6;22(10):2530-2540.

Garinet S., Laurent-Puig P., Blons H., Oudart JB. Current and Future Molecular Testing in NSCLC, What Can We Expect from New Sequencing Technologies? J Clin Med. 2018;7(6) pii: E144.

Karamanos NK, Piperigkou Z, Theocharis AD, Watanabe H, Franchi M, Baud S, Brézillon S, Götte M, Passi A, Vigetti D, Ricard-Blum S, Sanderson RD, Neill T, Iozzo RV. Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics. Chem Rev. 2018 Sep 26;118(18):9152-9232.

Salesse S., Odoul L., Chazée L., Garbar C. Duca L. Martiny L., Mahmoudi R., Debelle L. Elastin molecular aging promotes MDA-MB-231 breast cancer cell invasiveness. FEBS Open Bio. 2018 Aug 2;8(9):1395-1404


Boyé K., Pujol N., Alves I., Chen Y.P., Daubon T., Lee Y.Z., Dedieu S. Constantin M., Bello L., Rossi M., Bjerkvig R., Sue S.C., Bikfalvi A., Billottet C. LRP1 as a novel regulator of chemokine CXC Receptor-3 conformation, activity and trafficking: relevance for tumor cell invasion. Nature Communications 2017; 17;8(1):1571

Rybarczyk P, Vanlaeys A, Brassart B, Dhennin-Duthille I, Chatelain D, Sevestre H, Ouadid-Ahidouch H, Gautier M. The Transient Receptor Potential Melastatin 7 Channel Regulates Pancreatic Cancer Cell Invasion through the Hsp90α/uPA/MMP2 pathway. Neoplasia. 2017 ;19(4):288-300.

Pietraszek-Gremplewicz K, Karamanou K, Niang A, Dauchez M, Belloy N, Maquart FX, Baud S, Brézillon S. Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners? Matrix Biol sous presse.

Théret L., Jeanne A., Langlois B., Hachet C., David M., Khrestchatisky M., Devy J., Emonard H., Almagro S., Dedieu S. Identification of LRP-1 as an endocytosis and recycling receptor for β1-integrin in thyroid cancer cells. Oncotarget 2017; 8(45):78614-78632.

Karamanou K, Franchi M, Piperigkou Z, Perreau C, Maquart FX, Vynios DH, Brézillon S. Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition. Sci Rep. 2017; 7:45138.

Jeanne A., Untereiner V., Perreau C., Proult I., Boulagnon-Rombi C., Terryn C., Martiny L., Brezillon S., Dedieu S. Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide. Sci Rep., 2017; 7(1):7700 (2017).

Oudart JB, Monboisse JC, Maquart FX, Brassart B, Brassart-Pasco S, Ramont L. Type XIX collagen: A new partner in the interactions between tumor cells and their microenvironment. Matrix Biol. 2017; 57-58:169-177.

Verzeaux L., Belloy N., Thevenard-Devy J., Devy J., Ferracci G., Martiny L., Dedieu S., Dauchez M., Emonard H., Etique N., Devarenne-Charpentier E. Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons. Sci Rep. 2017; 7(1):5375.

Mohsen A, Collery P, Garnotel R, Brassart B, Etique N, Mohamed Sabry G, Elsherif Hassan R, Jeannesson P, Desmaële D, Morjani H. A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity. Metallomics. 2017 ;9(8):1176-1184.

Jeanne A, Rattenbach R, Lamensdorf I, Martiny L, Martin C, Dedieu S.  Thrombospondin-targeting TAX2 peptide impairs tumor growth in preclinical mouse models of childhood neuroblastoma. Pediatr. Res., 2017; 81(3):480-488.

Slimano F, Djerada Z, Bouchene S, Van Gulick L, Brassart-Pasco S, Dukic S. First plasma and tissue pharmacokinetic study of the YSNSG cyclopeptide, a new integrin antagonist, using microdialysis. Eur J Pharm Sci. 2017;105:178-187.

Appert-Collin A., Bennasroune A., Jeannesson P., Terryn C., Fuhrmann G., Morjani H., Dedieu S. Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix. Cell Adh Migr. 2017; 11(4):316-326.


Le Cigne A., Chieze L., Beaussart A., El-Kirat-Chatel S., Dufrêne Y.F., Dedieu S., Schneider C., Martiny L., Devy J., Molinari M. Analysis of the effect of LRP-1 silencing on the invasive potential of cancer cells by nanomechanical probing and adhesion force measurements using atomic force microscopy. Nanoscale 2016; 8(13):7144-54

Feru J, Delobbe E, Ramont L, Brassart B, Terryn C, Dupont-Deshorgue A, Garbar C, Monboisse JC, Maquart FX, Brassart-Pasco S. Aging decreases collagen IV expression in vivo in the dermo-epidermal junction and in vitro in dermal fibroblasts: possible involvement of TGF-β1. Eur J Dermatol. 2016;26(4):350-60.

Jeanne A., Boulagnon-Rombi C., Devy J., Théret L., Fichel C., Bouland N., Diebold M.D., Martiny L., Schneider C., Dedieu S. Matricellular TSP-1 as a target of interest for impeding melanoma spreading: towards a therapeutic use for TAX2 peptide. Clin. Exp. Metastasis 2016; 33:637-649

Galissier T., Schneider C., Nasri S., Kanagaratnam L., Fichel C., Coquelet C., Diebold M.D., Kianmanesh R., Bellon G, Dedieu S, Marchal-Bressenot A., Boulagnon-Rombi C. Biobanking of fresh-frozen human adenocarcinomatous and normal colon tissues: which parameters influence RNA quality? PlosOne 2016; 11(4):e0154326

Merghoub N, El Btaouri H, Benbacer L, Gmouh S, Trentesaux C, Brassart B, Terryn C, Attaleb M, Madoulet C, Benjouad A, Amzazi S, El Mzibri M, Morjani H. Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance. Nutr Cancer. 2016;68(1):131-43.

Bourguet E, Brazhnik K, Sukhanova A, Moroy G, Brassart-Pasco S, Martin AP, Villena I, Bellon G, Sapi J, Nabiev I. Design, Synthesis, and Use of MMP-2 Inhibitor-Conjugated Quantum Dots in Functional Biochemical Assays. Bioconjug Chem. 2016;27(4):1067-81.

Dekky B., Wahart A., Sartelet H., Fere M., Angiboust JF, Dedieu S., Piot O., Devy J., Emonard H. Cellular cholesterol distribution influences proteolytic release of the LRP-1 ectodomain. Front. Pharmacol. 2016; 12;7:25.

Stasiak M, Boncela J, Perreau C, Karamanou K, Chatron-Colliet A, Proult I, Przygodzka P, Chakravarti S, Maquart FX, Kowalska MA, Wegrowski Y, Brézillon S. Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity. PLoS One. 2016;11(3):e0150226.

Bagheri Varzaneh M, Rahmani H, Jahanian R, Mahdavi AH, Perreau C, Perrot G, Brézillon S, Maquart FX. Effects of Dietary Copper-Methionine on Matrix Metalloproteinase-2 in the Lungs of Cold-Stressed Broilers as an Animal Model for Pulmonary Hypertension. Biol Trace Elem Res. 2016;172(2):504-10.

Oudart JB, Doué M, Vautrin A, Brassart B, Sellier C, Dupont-Deshorgue A, Monboisse JC, Maquart FX, Brassart-Pasco S, Ramont L. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7(2):1516-28.

Emonard H., Duca L., Dedieu S. Matricellular receptors as potential targets in anti-cancer therapeutic strategies. Front. Pharmacol. 2016; 7:95.

Voir aussi dans «Matrice extracellulaire, Cancer et Cibles thérapeutiques»